Psoriasis or psoriasis is a chronic disease, the structure of the skin and its appendages: hair and nails. Characterized by periods of worsening condition (relapses) and temporal well-being, if the symptoms of the disease are becoming less and less. This disease is not contagious and the Patient is not a danger to others. Because of the emergence of psoriasis is not on micro-organisms.
Psoriasis often occurs within the age of 15-45 years. He is more prone to people with light skin. In developed countries, the number of Psoriasis patients achieved 2-4% of the population. Everyone suffers from a 25-year-old the inhabitants of the earth on all continents.
This Problem is a large number of medical facilities. So the psoriasis as the disease. But still the disease is not fully understood. Officially, it is considered incurable, and raises many questions.
Psoriasis is called the immune cells of the body. You rise from the lower to the upper layers of the skin, to inflammation, Proliferation of cells of the Epidermis and the formation of small capillaries.
Symptoms of psoriasis on the skin very differently. In most cases, this disease is the appearance of red patches psoriatic Plaques caused. They are dry to the touch, rise above the surface of the skin and the white flower is covered.
The disease is divided into two large groups: pustular and non-pustulous psoriasis.
In addition, such types of Psoriasis can
To the degree that such forms of Psoriasis can
To date, there are no clear-cut answer to the question: "why is psoriasis?" appears. Scientists have different theories.
Psoriasis is an autoimmune disease. Based on a malfunction of the immune system. Immune cells, the killer T cells and helper T cells, whose function is to protect the body against viruses, bacteria and tumor cells, for any reason, to penetrate into the upper layers of the skin. Here you will find produce inflammatory mediators – substances, the "shooting down" the inflammatory response. Your result is an increased cell division of the skin and its multiplication (Proliferation).
Psoriasis is keratinocytes, is a disease caused by the violation of growth, division and maturation of skin cells. The result of such changes in the skin, is an attack of immune cells, T-lymphocytes and macrophages to the diseased cells of the skin.
The doctors made a series of factors that can trigger the occurrence of the disease. Of course the majority of Psoriasis occurs when the body, a plurality of such conditions.
Psoriasis is a systemic disease that affects only the skin and nails. Of the joints, tendons, and spine, immune, nervous and endocrine system suffer. Often, the kidneys, the liver, the thyroid gland are affected. The Patient feels a strong weakness, suffer from chronic fatigue and Depression. Due to these complex effects on the organism, the disease in recent years, commonly referred to as the disease of Psoriasis.
But all the same basic symptoms of the disease occur on the skin layers. The name "psoriasis" conveys pretty accurately the symptoms of Psoriasis. The first manifestations are often the papules are pink or bright red, the correct rounded Form, covered with scales – psoriatic Plaques. They are symmetrical, the skin, especially on the extensor sides, the back and the head. But all the areas of the skin and mucus can beat skin of the genital organs. The size of a few millimeters, in the initial phase, up to ten centimeters and more.
Depending on the properties of the skin rash, taking such forms of Psoriasis:
Also, the shapes of the rash to distinguish, when its elements have the Form of rings, arches and garlands, cards with serrated edges.
Papules covered with bloom, which can be easily removed. It consists of dead cells of the Epidermis. Psoriasis Plaques start with scales from the center, then the Plaque spreads to the edges. Its casual and bright look due to the fact that the dead cells infused with filled intervals with air. The elements can be formed, Rosé Ring is a Phase of the inflammation, the platelet-derived growth zone. The skin around the elements of the rash has not changed.
Under the flowering undetectable smooth, shiny, bright red surface. These blood capillaries with thin walls, covered with thin foil. They are well visible because of the dilution of the upper layers of the skin. The normal structure of the skin is not disturbed, the cells, Mature keratinocytes, and do not have time to differentiate normal.
Psoriasis of the head Psoriasis Plaques, which protrude significantly, the surrounding skin is skin. They are densely covered with scales, reminiscent of the scales. The hair is not overwhelmed. Skin rashes can skin just under the hair, but also on the smooth, on the neck and behind the ears. These changes explain the active division of the keratinocytes on the affected areas
Psoriasis feet and hands causes a marked thickening of the Horny layer of the skin in these areas of the body. The skin is thick, rough. It is often by dragging cracks. This is an intensive division of cells that multiply 8 times faster than usual, but not deleted in a timely manner with the surface of the skin.
Psoriasis nails differs due to the variety of symptoms. But the greatest significance of the two main types of lesion of the nail plate:
Symptoms and signs of psoriasis depends on the stage of the disease, which follow one another cyclically in the course of the year. So in the case of most patients, there is the "Winter" type of the disease, when the degradation falls on the autumn and Winter. Improvement in the summer is due to the fact that UV light has the sun has a therapeutic effect. But some patients suffer from "summer" type.
Such a Phase of history can of Psoriasis:
Every body is different and reacts differently to the disease. So the nature of the lesions can be very different. This explains the diversity of forms and types of Psoriasis.
However, the majority of people have the symptoms of Psoriasis are similar. These patches of red psoriatic Plaques, 1-3 mm above the level of the healthy skin. Their formation is due to the fact that the cells of the surface layer of the skin – keratinocytes, not very actively, to tire coming to it, and a full-fledged skin cells. As a result of this increased pathological growth of the individual parts of the skin thicken. This occurs under the influence of the fact that the immune cells secrete chemicals that cause inflammation in the layers of the skin.
The spots are red. And if you have the top scales Psoriasis Plaques, then starts to the surface with the blood of Tau. This buckle is due to the fact that under the influence of T-lymphocytes and immune cells, which occurs in dendritic cells, the increased formation of new blood vessels under the metal. You have pretty thin walls. There may be bleeding psoriatic Plaques caused in the case of the slightest damage.
Sometimes, through the walls of these vessels, the lymph and the inflammatory exudate oozes. Here, bark on Blaschke thick, yellowish. Your surface damp to the touch.
The top tile can be covered in grey, silvery or yellowish Patina coated, which is a kind of Paraffin. That's how they got the name "Paraffin-lake". The dead skin cells, the rejection hurt, and they accumulate on the surface of the lesion of the skin.
Patches of flakes, more hot to the touch, than the Rest of the skin, can assume large proportions. Often the Patient is strong itching feeling at this point. This is due to the fact that on the background of the inflammatory process occurs in the cascade of Neuro-reflex reactions and allergic reaction.
A kind of elements of papules. These small elements of the rash are similar to tubercles. Size about 1 mm. In the middle is not a cavity, filled with content. Often they are on the knee and elbow joints. They remain even in times when the disease goes back.
The first Plaques form in those places where the skin is more dry and in contact with household chemicals and detergents – in the open areas of the hands, the neck. You can extremities on all parts of the body: on the scalp, face, trunk, genitals, buttocks,. In contrast to fungal diseases, Psoriasis outbreaks arise in the axils, and the natural folds, where the skin moist longer and oily. In some forms of the disease, there are only a few tokens does not increase in size. In the case of Palmar-plantar Form of defeat are only in these areas.
During the exacerbations of the elements of the rash gradually grow in width and merge with the neighboring tiles. In periods of improvement (Remission) patch start since the middle of educate. After the ring purchase form, and can disappear completely. According to the Plaques on the body there is a trace of pigmentation. It can be significantly lighter or darker than the surrounding areas of the skin. After the person suggests, the color of the skin usually evens out.